Aquaporina 1

Aquaporina 1 (grup sanguini Colton)
Estructures disponibles
PDB	Cerca a Ortholog: PDBe, RCSB
Llista de codis d'identif. PDB
	1FQY, 1H6I, 1IH5, 4CSK
Identificadors
Símbols	AQP1 ; AQP-CHIP; CHIP28; CO
Identif. externs	OMIM: 107776 MGI: 103201 HomoloGene: 68051 IUPHAR: Plantilla:IUPHAR GeneCards: AQP1 Gene
Ontologia genètica
Funció molecular	• intracellular cGMP activated cation channel activity; • potassium channel activity; • water transmembrane transporter activity; • protein binding; • ammonium transmembrane transporter activity; • potassium ion transmembrane transporter activity; • glycerol transmembrane transporter activity; • water channel activity; • glycerol channel activity; • transmembrane transporter activity; • nitric oxide transmembrane transporter activity; • carbon dioxide transmembrane transporter activity; • ephrin receptor binding;
Component cel·lular	• nucleus; • cytoplasm; • plasma membrane; • integral component of plasma membrane; • brush border; • basal plasma membrane; • basolateral plasma membrane; • apical plasma membrane; • symbiont-containing vacuole; • symbiont-containing vacuole membrane; • brush border membrane; • nuclear membrane; • sarcolemma; • axon terminus; • apical part of cell; • extracellular exosome;
Procés biològic	• renal water homeostasis; • glomerular filtration; • renal water transport; • cGMP biosynthetic process; • potassium ion transport; • water transport; • cell volume homeostasis; • cellular water homeostasis; • positive regulation of lamellipodium assembly; • positive regulation of epithelial cell migration; • carbon dioxide transport; • ammonium transport; • bicarbonate transport; • glycerol transport; • sensory perception of pain; • cellular homeostasis; • lateral ventricle development; • pancreatic juice secretion; • nitric oxide transport; • establishment or maintenance of actin cytoskeleton polarity; • cerebrospinal fluid secretion; • secretory granule organization; • cellular response to stress; • cellular response to UV; • transepithelial water transport; • carbon dioxide transmembrane transport; • wound healing; • odontogenesis; • response to drug; • hyperosmotic salinity response; • negative regulation of apoptotic process; • negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; • response to estrogen; • lipid digestion; • small molecule metabolic process; • positive regulation of angiogenesis; • positive regulation of saliva secretion; • positive regulation of fibroblast proliferation; • camera-type eye morphogenesis; • multicellular organismal water homeostasis; • corticotropin secretion; • transmembrane transport; • renal water absorption; • cellular response to hydrogen peroxide; • cellular response to inorganic substance; • cellular response to mechanical stimulus; • cellular response to copper ion; • cellular response to mercury ion; • cellular response to retinoic acid; • cellular response to cAMP; • cellular response to hypoxia; • cellular response to salt stress; • cellular hyperosmotic response; • cellular response to dexamethasone stimulus; • cellular response to nitric oxide; • potassium ion transmembrane transport; • metanephric descending thin limb development; • metanephric proximal straight tubule development; • metanephric proximal convoluted tubule segment 2 development; • metanephric glomerulus vasculature development; • ammonium transmembrane transport; • maintenance of symbiont-containing vacuole by host; • cation transmembrane transport;
	Fonts: Amigo / QuickGO
Patró d'expressió d'ARN
	More reference expression data
Ortòlegs
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L'aquaporina 1, o AQP1, és una aquaporina característica del ronyó. No està regulada per l'hormona antidiürètica (ADH), però associada bàsicament amb el ronyó, s'ha localitzat:

en el tub contornejat proximal
en la porció recta del túbul proximal
en la branca descendent estreta de la nansa de Henle

De manera addicional, també es troba en:

les cèl·lules vermelles de la sang
l'endoteli vascular
el tracte gastrointestinal
les glàndules sudorípares
els pulmons.^[1]

Referències[modifica]

↑ «Entrez Gene: AQP1 aquaporin 1 (Colton blood group)».

[1] «Entrez Gene: AQP1 aquaporin 1 (Colton blood group)».

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